No. S 439
Misuse of Drugs Act 1973
Misuse of Drugs
(Amendment) Regulations 2022
In exercise of the powers conferred by section 58 of the Misuse of Drugs Act 1973, the Minister for Home Affairs makes the following Regulations:
Citation and commencement
1.  These Regulations are the Misuse of Drugs (Amendment) Regulations 2022 and come into operation on 1 June 2022.
Amendment of First Schedule
2.  In the First Schedule to the Misuse of Drugs Regulations (Rg 1), in paragraph 1, replace sub‑paragraph (2) with —
(2)  The substances to which this paragraph applies are acetyldihydrocodeine, codeine, dihydrocodeine, ethylmorphine, nicocodine, nicodicodine (6-nicotinoyldi-hydrocodeine), norcodeine, pholcodine and their respective salts.”.
Amendment of Fourth Schedule
3.  In the Fourth Schedule to the Misuse of Drugs Regulations —
(a)in paragraph 15, delete item (2);
(b)in paragraph 15, after item (6), insert —
“(6A)
1-(1,3-Benzodioxol-5-yl)-2-(pyrrolidin-1-yl)hexan-1-one (also known as 3,4-Methylenedioxy-α-pyrrolidinohexanophenone or 3,4-MDPHP)”;
(c)in paragraph 15, after item (8AA), insert —
“(8AAAA)
2-(Butylamino)-1-phenylhexan-1-one (also known as N-Butylhexedrone or α‑Butylaminohexanophenone)”;
(d)in paragraph 17, after item (2A), insert —
“(2B)
N-(1-Amino-3,3-dimethyl-1-oxobutan-2-yl)-5-bromo-1H-indazole-3-carboxamide (also known as ADB-5-Bromo-INACA) and its bromo positional isomers in the 6-membered ring of the indazole structure”;
(e)in paragraph 17, after item (6G), insert —
“(6H)
1-(1-(1-(4-Bromophenyl)ethyl)-piperidin-4-yl)-1,3-dihydro-2H-imidazol-2-one (also known as Brorphine) and its bromo positional isomers in the phenyl ring”;
(f)in paragraph 17, after item (8B), insert —
“(8C)
2-(1-(Cyclohexylmethyl)-2-oxo-1,2-dihydro-3H-indol-3-ylidene)benzohydrazide (also known as N’-(1-(Cyclohexylmethyl)-2-oxoindolin-3-ylidene)benzohydrazide or BZO-CHMOXIZID)”;
(g)in paragraph 17, after item (10C), insert —
“(10D)
N,N-Diethyl-2-(2-(4-methoxybenzyl)-5-nitro-1H-benzo[d]imidazol-1-yl)ethan-1-amine (also known as Metonitazene) and its diethylamino structural isomers and their respective methoxy positional isomers in the phenyl ring and nitro positional isomers in the 6-membered ring of the benzimidazole structure”;
(h)in paragraph 17, after item (19), insert —
“(19AA)
N-Ethyl-1-(3-fluorophenyl)propan-2-amine (also known as 3-Fluoroethamphetamine, 3‑Fluoroethylamphetamine or 3-FEA) and its fluoro positional isomers in the phenyl ring”;
(i)in paragraph 17, after item (19A), insert —
“(19ABD)
2-(2-(1-(4-Fluorobenzyl)-1H-(6-hydroxyindol)-3-yl)acetamido)-3,3-dimethylbutanamide and its N‑(1-amino-1-oxohexan-2-yl) isomers and their respective fluoro positional isomers in the phenyl ring and hydroxy positional isomers in the 6‑membered ring of the indole structure
(19ABE)
2-(2-(1-(4-Fluorobenzyl)-1H-indol-3-yl)acetamido)-3,3-dimethylbutanamide (also known as ADB-FUBIATA or FUB-ACADB or AD-18) and its N-(1-amino-1-oxohexan-2-yl) isomers and their respective fluoro positional isomers in the phenyl ring”;
(j)in paragraph 17, before item (20AB), insert —
“(20)
2-(1-(5-Fluoropentyl)-2-oxo-1,2-dihydro-3H-indol-3-ylidene)benzohydrazide (also known as N’-(1-(5-Fluoropentyl)-2-oxoindolin-3-ylidene)benzohydrazide or 5-Fluoro-BZO-POXIZID or 5F-BZO-POXIZID or MDA-19 5-fluoropentyl analogue or 5F-MDA-19) and its fluoro positional isomers in the pentyl group”;
(k)in paragraph 17, after item (22), insert —
“(22A)
2-(1-Hexyl-2-oxo-1,2-dihydro-3H-indol-3-ylidene)benzohydrazide (also known as N’-(1-Hexyl-2-oxoindolin-3-ylidene)benzohydrazide or BZO-HEXOXIZID or MDA-19)”;
(l)in paragraph 17, after item (25), insert —
“(25A)
2-(1-(5-Hydroxyhexyl)-2-oxo-1,2-dihydro-3H-indol-3-ylidene)benzohydrazide (also known as N’-(1-(5-Hydroxyhexyl)-2-oxoindolin-3-ylidene)benzohydrazide) and its hydroxy positional isomers in the hexyl group”;
(m)in paragraph 17, after item (27), insert —
“(27AAA)
2-(1-(5-Hydroxypentyl)-2-oxo-1,2-dihydro-3H-indol-3-ylidene)benzohydrazide (also known as N’-(1-(5-Hydroxypentyl)-2-oxoindolin-3-ylidene)benzohydrazide) and its hydroxy positional isomers in the pentyl group”;
(n)in paragraph 17, after item (36), insert —
“(36A)
2-(1-Pentyl-2-oxo-1,2-dihydro-3H-indol-3-ylidene)benzohydrazide (also known as N’-(1-Pentyl-2-oxoindolin-3-ylidene)benzohydrazide or BZO-POXIZID or MDA-19 pentyl analogue or 5C-MDA-19)”;
(o)in paragraph 17, after item (37), insert —
“(38)
1-Phenyl-2-phenyl-2-(1-pyrrolidinyl)ethanone (also known as α-Pyrrolidino-2-phenylacetophenone or α-D2PV)”;
(p)in paragraph 19, after item (50), insert —
“(51)
(1-(Pent-4-en-1-yl)-1H-indol-3-yl)(2,2,3,3-tetramethylcyclopropyl)methanone (also known as XLR-11 N-(4-pentenyl) analogue or UR-144 N-(4-pentenyl) analogue)”;
(q)in paragraph 20, after item (9), insert —
“(9A)
4-{3-[(1-Adamantyl)carbamoyl]-1H-indazole-1-yl}butanoic acid”; and
(r)in paragraph 20, after item (36), insert —
“(36AA)
2-[1-(5-Fluoropentyl)-1H-indole-3-carboxamido]-3-methylbutanoic acid”.
[G.N. Nos. S 390/99; S 231/2000; S 436/2000; S 140/2001; S 492/2001; S 506/2005; S 490/2006; S 108/2007; S 525/2010; S 684/2010; S 270/2013; S 322/2014; S 571/2014; S 253/2015; S 199/2016; S 193/2017; S 234/2018; S 588/2018; S 88/2019; S 151/2019; S 353/2019; S 791/2019; S 350/2020; S 750/2020; S 283/2021; S 939/2021]
Made on 28 May 2022.
PANG KIN KEONG
Permanent Secretary,
Ministry of Home Affairs,
Singapore.
[MHA 112/2/0049; AG/LEGIS/SL/185/2020/7 Vol. 1]